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<h1>Operon</h1>
<ul>
	<li><a href="#descrition">Brief Description</a></li>
	<li><a href="#scope">Scope</a></li>
	<li><a href="#access">Data Access</a></li>
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<h2><a name="description"/>Brief Description</h2>

Since 1998 the <a  href="http://www.cng.fr/">Centre National de Genotypage (CNG)</a> has been involved in hundreds of international genetics projects dealing with diverse environmental, biomarker and genetic data directed for the most part to study genes and human diseases.
These projects have lead to the development of the Operon system, a feasible bioinformatics platform to centralize scientific software and biomedical data with internal results.
In this website, some of the Operon's functionalities are provided with the aim to give access to genotyping data produced at the CNG.
The system is under development, and a more formal release will be further noticed.
For more information or comments, please send email to operon@cng.fr.
<h2><a name="scope"/>Scope</h2>

 This website interfaces the Operon databases and software tools needed to search and export genotype data with their associated annotations. By sequence alignment and algorithmic database analyses, the CNG genotype data is integrated with fundamental genomic and genetic public data sets. Most notably these resources are: <a class="key" href="http://www.ncbi.nlm.nih.gov/genome/guide/human/">NCBI Human Genome Assembly build 36</a>, <a class="key" href="http://www.ncbi.nlm.nih.gov/RefSeq/">Reference Sequences (RefSeq)</a>, <a class="key" href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene">Entrez Genes DB</a>, <a class="key" href="http://www.ncbi.nlm.nih.gov/SNP/index.html">dbSNP</a>, <a class="key" href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=unists">UniSTS</a>, <a class="key" href="http://www.nature.com/nature/journal/v380/n6570/abs/380152a0.html">Genethon</a>, <a class="key" href="http://www.decode.com/">deCODE</a>, <a class="key" href="http://research.marshfieldclinic.org/genetics/home/index.asp">Marshfield</a>, <a class="key" href="http://www.illumina.com/">Illumina SNP panels</a>, <a class="key" href="http://www.affymetrix.com/">Affymetrix SNP panels</a>, and the <a class="key" href="http://www.hapmap.org/">HapMap Project databases</a>. The NCBI Human Genome Assembly build 36 is used to normalize all genomic data into the same physical map reference. The RefSeq data sets provide non-redundant and annotated genomic DNA, transcript (RNA), and protein sequence records. These sequences are cross-referenced with the Entrez Gene and UniSTS genomic loci. Some of these loci correlate with the Marshfield, deCODE, and the Genethon genetic maps. All these data sets are interconnected and controlled by the Operon system with the aim to allow researchers further investigate about 1x10<sup>7</sup> polymorphisms, and 4x10<sup>9</sup> genotypes currently available throughout this website.

<h2><a name="access"/>Data Access</h2>

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